Where chlamydial or gonococcal infection is suspected, antibiotics effective against chlamydia, notably a tetracycline, are usually combined with an antigonococcal agent. In severe disease, intravenous or oral tetracycline and intravenous therapy with a penicillin or cephalosporin should be given until the patient can tolerate oral therapy. In less seriously ill patients, oral regimens may be used. The possibility of infection by anaerobic bacteria should be considered in a patient in whom no organism has been identified or who has had previous episodes. Some antibiotics are contraindicated in pregnancy. Tetracyclines are contraindicated in pregnancy and in children under the age of 8 years. No effective single dose regimen is available for treatment of chlamydial or mycoplasmal infections.
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